Ellen Burstyn, Requiem for a Dream (2000) directed by Darren Aronofsky and starring Ellen Burstyn, Jared Leto, Jennifer Connelly, and Marlon Wayans. The film is based on the novel of the same name by Hubert Selby, Jr., with whom Aronofsky wrote the screenplay. Burstyn was nominated for an Academy Award for Best Actress for her performance as Sara Goldfarb, a self destructive, delusional train-wreck. Julia Roberts, Erin Brockovich took home the award instead