San Francisco Mayor London Breed talks about the first confirmed case of the omicron variant during a COVID-19 briefing outside City Hall in San Francisco, Wednesday, Dec. 1, 2021. The U.S. recorded its first confirmed case of the omicron variant Wednesday — a person in California who had been to South Africa. Genomic sequencing on the patient's virus was conducted at the University of California, San Francisco. (AP Photo/Eric Risberg)
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