This artist's rendering provided by Wexford Science & Technology shows plans for an expansion of the Cortex innovation hub in St. Louis, home to several start-up businesses. The city's image has taken a hit in recent years due to factors such as racial protests, the loss of the NFL's Rams and the departure of several Fortune 500 companies. But civic leaders see renewed hope in St. Louis' growing start-up scene, especially firms connected to the region's strength in medicine and science. (Wexford Science & Technology via AP)
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