Germany's Angelique Kerber reacts after missing a shot when losing in two sets, 2-6, 2-6, against Russia's Ekaterina Makarova at the French Open tennis tournament at the Roland Garros stadium in Paris, France, Sunday, May 28, 2017. Angelique Kerber is the first women's No. 1 seed to lose in the French Open's first round in the Open era.(AP Photo/Petr David Josek)
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