49es take on former QB Alex Smith, Washington

WASHINGTON (5-7) vs. SAN FRANCISCO (5-7), at Glendale, Arizona

Sunday, 4:25 p.m. ET, Fox

OPENING LINE - 49ers by 4

RECORD VS. SPREAD - Washington 6-4-2; 49ers 5-7

SERIES RECORD - 49ers led 21-11-1

LAST MEETING - 49ers beat Washington 9-0 on road, Oct. 20, 2019

LAST WEEK - Washington beat Steelers 23-17; 49ers lost to Bills 34-24

AP PRO32 RANKING - Washington No. 19, 49ers No. 20

WASHINGTON OFFENSE - OVERALL (26), RUSH (24), PASS (25).

WASHINGTON DEFENSE - OVERALL (4), RUSH (10), PASS (3).

49ERS OFFENSE - OVERALL (14), RUSH (18), PASS (13).

49ERS DEFENSE - OVERALL (6), RUSH (9), PASS (10).

STREAKS, STATS AND NOTES - Washington has won five of six in the series. … Washington started 1-5 but is now on a three-game winning streak. … Washington’s defense gave up a 50-yard TD pass last week, the 10th play of 40 yards or more it has allowed through the air, tied with the Los Angeles Chargers for the most in the NFL this season. … Washington’s past three opponents have combined to score a total of six points in the second half. … Rookie RB Antonio Gibson (659 yards), who injured a toe in Washington’s last game, is the team’s only player with more than 250 yards rushing this season. … Washington was unable to sack Pittsburgh QB Ben Roethlisberger in Week 13, but DE Montez Sweat tipped three passes, including one that was intercepted with about 2 minutes left to help seal the win. … Washington has scored 20 or more points in its past half-dozen games; if it reaches that mark against San Francisco, it would give the team a seven-game run for the first time since Weeks 1-8 of the 1999 season. … Washington QB Alex Smith will make his second start against the 49ers, who drafted him first overall in 2005. The only teams Smith hasn’t beaten in his career are San Francisco and Kansas City. … The Niners are playing their second straight home game in Arizona after being kicked out of their stadium because of COVID-19 protocols that ban contact sports in Santa Clara County for three weeks. … The 49ers have committed at least two turnovers in six straight games, the longest active streak in the NFL and the longest for San Francisco since an eight-game streak in 2008. … Niners QB Nick Mullens threw for 316 yards and three TDs last week for his fourth career 300-yard passing game and third with at least three TDs. … Niners LT Trent Williams and TE Jordan Reed face Washington for the first time after beginning their careers there. … San Francisco has allowed a passer rating of at least 125 a league-worst four times this season, but is also tied with the most games holding opponents to a rating less than 60 with three. … The 49ers averaged 6.7 yards per play last week, their third-highest mark in a loss in four seasons under coach Kyle Shanahan. … San Francisco LB Fred Warner needs nine tackles for his third straight 100-tackle season. … Fantasy tip: Niners rookie WR Brandon Aiyuk had five catches for 95 yards and one TD last week. He has TDs in three straight games and at least five catches for 75 yards in four in a row.

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