By Associated Press - Friday, January 26, 2018

MADRID (AP) - Real Madrid will be without central defender Sergio Ramos and midfielder Isco for Saturday’s Spanish league match at Valencia because of injury.

Madrid said on Friday that Ramos has pulled a muscle in his left leg, while Isco has a pinched nerve in his left thigh.

Madrid is in a fight to ensure a top-four finish. It trails third-place Valencia by five points - albeit with a game in hand - and has Villarreal one point behind in fifth.

Madrid visits Valencia’s Mestalla Stadium three days after a shock loss to Leganes sent it tumbling out of the Copa del Rey quarterfinals.

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