- Associated Press - Friday, June 10, 2011

BERLIN (AP) - Investigators have determined that German-grown vegetable sprouts are the cause of the E. coli outbreak that has killed 29 people and sickened nearly 3,000, the head of Germany’s national disease control center said Friday.

Reinhard Burger, president of the Robert Koch Institute, said even though no tests of the sprouts from an organic farm in Lower Saxony had come back positive for the E. coli strain behind the outbreak, an investigation into the pattern of the outbreak had produced enough evidence to draw the conclusion.

“In this way, it was possible to narrow down epidemiologically the cause of the outbreak of the illness to the consumption of sprouts,” Burger said at a press conference with the heads of Germany’s Federal Institute for Risk Assessment and Federal Office for Consumer Protection. “It is the sprouts.”

The breakthrough in the investigation came after a task force from the three institutes linked separate clusters of patients who had fallen sick to 26 restaurants and cafeterias that had received produce from the organic farm.

“It was like a crime thriller where you have to find the bad guy,” said Helmut Tschiersky-Schoeneburg from the consumer protection agency.

“They even studied the menus, the ingredients, looked at bills and took pictures of the different meals, which they then showed to those who had fallen ill,” said Andreas Hensel, head of the Risk Assessment agency.

Hensel said authorities were lifting the warning against eating cucumbers, tomatoes and lettuce, and explicitly urged consumers to start eating those vegetables once again.

“Lettuce, tomatoes and cucumbers should be eaten again _ it is all healthy produce,” he said.

Burger said it was possible that all of the tainted sprouts have either been consumed or thrown away by now, but still warned that the crisis is not yet over and people should not eat sprouts.

While the farm in the northern German village of Bienenbuettel that has been blamed for the outbreak was shut down last Thursday and all of its produce recalled, the experts said they could not exclude the possibility that some tainted sprouts were still being used by restaurants or cafeterias and people could still get infected with E. coli.

Also, since it has not yet be established why the sprouts were bad _ whether the seeds had been contaminated or the farm’s water _ the experts said it was possible that other nearby farms could also be affected.

Germany has been the epicenter of the outbreak, with 2,808 sickened, 722 of whom are suffering from a serious complication that can cause kidney failure. The World Health Organization says 97 others have fallen sick in 12 other European countries, as well as three in the United States.

In recent days the numbers of people being reported ill have been dropping, but it was not clear whether the epidemic was waning or consumers were just successfully shunning tainted vegetables.

David Acheson, former chief medical officer of the U.S. Food and Drug Administration, told NPR’s All Things Considered that tests proving the exact source of an E. coli investigation are often elusive, so conclusions have to be drawn from the pattern of the outbreak.

“We, in the U.S., reacted many times appropriately to solid epidemiology without actually having a positive sample, like spinach in 2006, which was obviously a massive E. coli outbreak,” he said.

The sprouts were initially blamed for the outbreak on Sunday, but authorities backpedaled the following day after lab tests came in negative and there was not yet enough epidemiological evidence.

During the course of the investigation, non-lethal E. coli was also found on cucumbers from Spain and beet sprouts from the Netherlands.

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